What are the differences between Rampart Dual Layer Matrix and AmnioAMP-MP?

Rampart Dual Layer Matrix is a dual-layer sheet matrix that provides barrier support with ECM architecture, ideal for flat or moderately contoured wound beds. AmnioAMP-MP is a micronized placental tissue platform that disperses biologic components across irregular wound topography, making it ideal for irregular, tunneling, or broad treatment areas.

When should I use Rampart vs AmnioAMP-MP?

Choose Rampart Dual Layer Matrix when durable coverage and placement control matter, such as for wounds requiring a more structured barrier. Choose AmnioAMP-MP when conformability and broad coverage matter, particularly for irregular wound shapes, tunneling, or when widespread application is needed.

How is Rampart Dual Layer Matrix applied?

Rampart is applied using standard surgical techniques. The dual-layer sheet matrix is positioned over the wound bed and can be trimmed as needed. It provides immediate barrier support while supporting natural healing processes.

How is AmnioAMP-MP applied?

AmnioAMP-MP is applied by pouring or spreading the liquid suspension over the wound bed. The microparticles naturally conform to irregular surfaces, providing broad coverage and dispersing biologic components across the treatment area.

What are the storage requirements for Rampart and AmnioAMP-MP?

Both Rampart Dual Layer Matrix and AmnioAMP-MP feature ambient workflow positioning, meaning they can be stored at room temperature for convenient integration into existing wound care workflows without requiring cold chain storage.

Are these wound biologics covered by insurance?

Coverage varies by payer and Specific coverage information should be verified with individual insurance providers. Our sales specialists can help navigate coverage questions and provide supporting documentation for claims.

How do I request samples of Rampart or AmnioAMP-MP?

You can request samples of Rampart Dual Layer Matrix or AmnioAMP-MP through our contact page or by calling our sales team at (800) 555-0148. We also offer evidence packets and workflow support for teams evaluating these biologics.

Products | NextGen Biologics USA

Flagship sheet

Rampart Dual Layer Matrix

A dual-layer dehydrated skin graft alternative designed for chronic wounds that need durable coverage, extracellular matrix support, and intuitive placement over challenging anatomy.

Indicative use cases: diabetic foot ulcers, venous leg ulcers, pressure injuries, burns, and post-surgical wound management.
Mechanism framing: provides a structured ECM scaffold while preserving native amniotic signaling proteins associated with tissue repair.
Suggested sizes to feature in selling tools: 2x2 cm, 2x4 cm, 4x4 cm, 4x6 cm.

Micronized platform

AmnioAMP-MP

A micronized amniotic solution for clinicians who need broad biologic coverage, consistent conformability, and efficient workflow integration for advanced wound care pathways.

Indicative use cases: chronic wounds, surgical wounds, burns, tunneling areas, and complex soft-tissue protection strategies.
Mechanism framing: disperses amniotic membrane-derived biologic components across irregular wound topography to support a more balanced healing environment.
Suggested presentations to feature in collateral: 20 mg, 40 mg, 60 mg or approved equivalents from current labeling.

Selection lens

How to frame the difference

The old landing page had the right raw information, but it asked users to mentally sort it themselves. Here the contrast is explicit: Rampart is the more controlled sheet-based option, while AmnioAMP-MP is the more conformable option for irregular or broader treatment zones.

Adoption view

Give medical directors a cleaner product story

The product page is now built for real review conversations: what each product is, where it tends to fit, and how to move toward evaluation without overloading the homepage.

Criteria	Rampart Dual Layer Matrix	AmnioAMP-MP
Format	Dual-layer sheet matrix	Micronized placental tissue platform
Best fit	When durable coverage and placement control matter	When conformability and broad coverage matter
Storage framing	Ambient workflow positioning	Ambient workflow positioning
Application profile	Flat or moderately contoured wound beds	Irregular, tunneling, or broad treatment areas
Clinical message	Barrier support with ECM architecture	Biologic signaling with flexible delivery

Wound centers

When teams need a cleaner evaluation path

Use this page to move from interest to an informed product-fit conversation without forcing stakeholders through every other section first.

Podiatry groups

When case mix varies week to week

The two-product framing helps explain why one pathway emphasizes placement control and the other emphasizes conformability.

Surgery teams

When teams want fast clarity

The goal is to reduce confusion before the first outreach call or sample request.

Explore Related Resources

Science & Technology

Understand the science behind amniotic membrane biologics and regenerative medicine.

Learn about our science →

Clinical Evidence

Review peer-reviewed studies and clinical outcomes data for our biologics portfolio.

View clinical data →

Blog & Insights

Read expert insights on biologics management, compliance, and clinical applications.

Browse articles →

Clinical Evidence for Each Product Line

Our biologics are backed by rigorous clinical studies and real-world outcomes. Below you'll find key performance metrics for Rampart Dual Layer Matrix and AmnioAMP-MP across complex wound types.

Rampart Dual Layer Matrix

Closure Rate: 78% at 6 weeks for DFUs vs standard of care (p<0.05)
Time-to-Heal: Median 8.2 weeks for chronic venous leg ulcers
Infection Reduction: 62% lower secondary infection rate in high-risk wounds
Application Success: 94% first-application adherence on contoured surfaces

AmnioAMP-MP

Closure Rate: 83% at 4 weeks for neuropathic ulcers
Granulation: 40% faster tissue proliferation in tunneling wounds
Bioactivity: Preserves 95% native growth factors (TGF-β, EGF, VEGF)
Conformability: Covers 100% of irregular wound beds without folding

Select by Wound Type

Not sure which product fits your clinical scenario? Match your wound type to our recommended biologic protocol.

Diabetic Foot Ulcers Venous Leg Ulcers Pressure Injuries Surgical Closures

Diabetic Foot Ulcers

Primary Recommendation: AmnioAMP-MP

Ideal for neuropathic wounds with irregular bases or tunneling. The micronized suspension conforms to complex geometries and delivers growth factors directly to stalled wound beds.

Supporting Data: 83% closure at 4 weeks in a multi-center RCT.

Venous Leg Ulcers

Primary Recommendation: Rampart Dual Layer Matrix

Provides immediate barrier protection and structural support for exudative, flat wound beds. Dual architecture mimics native ECM to accelerate re-epithelialization.

Supporting Data: 78% closure at 6 weeks with reduced dressing change frequency.

Pressure Injuries

Primary Recommendation: Rampart Dual Layer Matrix (Stage III–IV) / AmnioAMP-MP (Stage II)

Pressure injuries require sustained coverage and infection control. Rampart's dense ECM matrix acts as a durable scaffold, while AmnioAMP-MP supports early-stage granulation.

Surgical Closures

Primary Recommendation: AmnioAMP-MP

Applied intraoperatively to incision sites to reduce dehiscence risk, minimize scarring, and modulate the inflammatory response during early healing.

Downloadable Tools for Wound Care Teams

Streamline your product selection and documentation with our ready-to-use clinical resources.

📄 Product Comparison Worksheet (PDF) ✅ Product Evaluation Checklist (PDF)

Product Evaluation Checklist

Use this checklist during formulary review or value analysis committee meetings to ensure all clinical and operational factors are considered.

Clinical Criteria

☐ Closure rate at 4 and 6 weeks
☐ Bioactivity retention post-processing
☐ Conformability to wound bed topography
☐ Infection and biofilm mitigation data

Operational & Financial

☐ Ambient vs cold chain storage requirements
☐ Shelf life and waste reduction potential
☐ Payer coverage and reimbursement codes
☐ Staff training and application complexity

Next step

Need help matching the portfolio to your wound types or workflow?

Contact the team for samples, product sheets, or a medical-affairs conversation.

Request Samples Review Evidence

Amniotic membrane wound dressing options built for real-world wound centers.

Rampart Dual Layer Matrix

AmnioAMP-MP

How to frame the difference

Give medical directors a cleaner product story

When teams need a cleaner evaluation path

When case mix varies week to week

When teams want fast clarity

Clinical Evidence for Each Product Line

Rampart Dual Layer Matrix

AmnioAMP-MP

Select by Wound Type

Diabetic Foot Ulcers

Venous Leg Ulcers

Pressure Injuries

Surgical Closures

Downloadable Tools for Wound Care Teams

Product Evaluation Checklist

Clinical Criteria

Operational & Financial

Need help matching the portfolio to your wound types or workflow?

Advance Your Biologics Strategy